Byculla or Bhaykhala is a neighbourhood in South Mumbai. It is also the name of a railway station on the Mumbai suburban railway on the Central Railway line.

Byculla, like many other locations of Mumbai have witnessed strong real estate growth, particularly in the Motisha Lane area where there are lots of tall residential buildings, occupied by affluent Jain community.

Byculla has also witnessed the increase of population of Dawoodi Bohra and other traditional Muslims, who are primarily a business community like most of the Gujaratis.

There is also a BIT Chawl, primarily housing Marathi working class community, home to one of the largest Ganesha idols during the Ganeshotsav celebrations. Byculla is also known for Mumbai's first ever "Y-bridge" built across Dr. Babasaheb Ambedkar Road which then splits further to go to Byculla East and West before the Clare Road intersection, thereby forming a Y shape when seen from the air. This was one of the oldest fly-overs built in Mumbai.

Mumbai Fire Brigade's headquarters are situated just below the "Y Bridge". In the front of the Headquarter building, there is a memorial built in the memory of numerous fire fighters who died during the Bombay Explosion (1944) of April, 1944.
Jerbai Baug and Rustom Baug: are the two Parsi colonies where most of the Parsis of Byculla live.

Byculla is very well connected by Central Railway line of the Mumbai Suburban Railway, as well as Bus routes serviced by BEST. In fact, most of the buses servicing South Mumbai, South-Central Mumbai, Central Mumbai and North-East Mumbai pass through Byculla. It was this heavy traffic which had prompted city planners to develop major fly-overs in Byculla, as early as 1980s.

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